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Public Article
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ACE Gene Polymorphism in Hypertension Patients from District Kohat
ISSN: 2195-1381
Publisher: author
ACE Gene Polymorphism in Hypertension Patients from District Kohat
Indexed in
Science General
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-1402
Publisher: Direct Sciences
eISSN
:
2195-1381
Abstract
Hypertension, an outstanding danger factor for different cardiovascular, fringe vascular and renal occasions is a significant general wellbeing challenge. Reninangiotensin framework being the most essential pathogenic system of hypertension is interceded by a key segment, the angiotensin converting enzyme. The aim of current study was to know the relationship of hypertensive patients with angiotensin converting enzyme gene polymorphism. Total 65 clinically analyzed hypertensive patients with no related sickness condition and five age and sex coordinated clearly sound controls were included in the current study. Polymerase chain reaction was used for the amplification of intron number 16 of Angiotensin converting enzy megene harboring the 287 bp Alu repeat sequence. Homozygous Deletion/Deletion, Insertion/Insertion and heterozygous Insertion/Deletion were the three possible genotypes which were analyzed. After the amplification of prod...
