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DNA Topoisomerases as Targets for Anticancer Agents
ISSN: 2687 - 5365
Publisher: author
DNA Topoisomerases as Targets for Anticancer Agents
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-1702
Publisher: International Journal Of Academic Medicine And Pharmacy Ne..
International Journal Address (IAA):
IAA.ZONE/268771275365
eISSN
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2687 - 5365
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Abstract
Cancer is a complex disease resulting from various genetic changes that lead to disorders in the mechanisms regulating the basic functions of the cell. As a result of these genetic changes, it is a disease characterized by the fact that new cancer cells are constantly formed and cannot be destroyed by disrupting the cell cycle. Cancer is one of the main causes of deaths worldwide. It causes approximately 9 million deaths annually. Many different treatment modalities are applied in cancer treatment to decrease mortality and increase survival. There are three main approaches in cancer treatment: chemotherapy, radiotherapy and surgical methods. In chemotherapy, which is the most commonly used method among these, while apoptosis of cancer cells is targeted with chemical agents, it is also prevented from stopping the cancer by spreading. However, new approaches to cancer treatment are still being investigated today, since existing drugs ca...
