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Study of eosinophil cationic protein serum levels in patients with toxocariasis
ISSN: 2695 - 5075Publisher: author   
Study of eosinophil cationic protein serum levels in patients with toxocariasis
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Medical Sciences
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1.3
Article Basics Score: 3
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International Category Code (ICC):
ICC-1702
Publisher: Iberoamerican Journal Of Medicine Iberoamerican Journal Of..
International Journal Address (IAA):
IAA.ZONE/269557015075
eISSN
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2695 - 5075
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Abstract
Introduction: Toxocariasis is a zoonotic helminth infection with difficult diagnosis. Determination of specific IgG antibodies alone does not allow to establish the disease stage and to evaluate the treatment efficacy. Therefore it is necessary to identify additional markers that will assist the diagnosis. The purpose of our study was to identify and monitor eosinophil cationic protein (ECP) levels in patients with toxocariasis confirmed by serology and to compare our data with the literature to determine the relevance of this protein as an indicator for recent infection and the effectiveness of the therapy. Material and methods: ELISA (CUSABIO) commercial kit was used for determination of ECP concentration. Sixty serum samples were studied from individuals previously tested and confirmed for toxocariasis by the presence of specific anti-Toxocara IgG antibodies in ELISA (Toxocara IgG Rbiopharm) and the presence of specific bands in We...