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Bilirubin in Diabetic Retinopathy: Too Little or Too Much?
ISSN: 2319 - 2453
Publisher: author
Bilirubin in Diabetic Retinopathy: Too Little or Too Much?
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: Dr. Prabhakar Puttachandra
International Journal Address (IAA):
IAA.ZONE/2319405262453
eISSN
:
2319 - 2453
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Abstract
Diabetic retinopathy (DR) is a significant diabetic complication that may result in loss of vision and blindness. The development of DR is intricate and encompasses numerous processes, such as oxidative stress. Bilirubin, a powerful antioxidant, has been proposed as a probable indicator for oxidative stress in DR. Bilirubin is a powerful antioxidant that helps to eliminate free radicals and other reactive oxygen species (ROS) in the body by being produced during the breakdown of heme. Additionally, it aids in the regulation of the expression of antioxidant genes, further bolstering its antioxidant properties. Therefore, bilirubin plays a crucial role in safeguarding cells from oxidative stress. Oxidative stress arises when there is an imbalance between ROS production and the body's ability to detoxify them. This can result in oxidative damage to cellular components like proteins, lipids, and DNA. Oxidative stress has been implicated i...
