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Unusual Case of Pyoderma Gangrenosum and Bilateral Ear Changes Secondary to the Use of Cocaine with Levamisole in a Pa...
ISSN: 2582 - 6751
Publisher: author
Unusual Case of Pyoderma Gangrenosum and Bilateral Ear Changes Secondary to the Use of Cocaine with Levamisole in a Pa...
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Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: Athenaeum Scientific Publishers
International Journal Address (IAA):
IAA.ZONE/2582117476751
eISSN
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2582 - 6751
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Abstract
Abstract The knowledge of skin as well as ear complications caused by cocaine with levamisole is evolving. We described a patient with primary autoimmune rheumatological disorder- Systemic Lupus Erythematosus (SLE) as well as Chronic Hepatitis C and Pyoderma Gangrenosum (PG) as well as ear changes which might be in differential diagnosis of Relapsing Polychondritis (RP). Also the patient had positive P- ANCA and C- ANCA antibodies as well as elevated titers of ANA and decreased complement levels of C3, C4, CH50. Although pyoderma gangrenosusm is described in patients with SLE, hepatitis C etc. the time course of consumption of cocaine with levamisole as well antibody changes described were typical for drug induced ear changes and pyoderma gangrenosum. We think clinicians should always include the urine/ blood drug test when dealing with those disorders to exclude drug induced pyoderma gangrenosusum and ear changes, before attributing ...
