×
Suggest this Article to:
TOP INDEXERS
Public Article
-
verified
The Genetic Discrepancy-Lynch Syndrome
ISSN: 2582 - 6751
Publisher: author
The Genetic Discrepancy-Lynch Syndrome
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: Athenaeum Scientific Publishers
International Journal Address (IAA):
IAA.ZONE/2582117336751
eISSN
:
2582 - 6751
VALID
ISSN Validator
Abstract
Lynch syndrome is a frequently discerned hereditary cancer syndrome demonstrating the occurrence of colorectal carcinomas in around 80% subjects and endometrial cancers in nearly 60% individuals. Lynch syndrome is accompanied by germ line chromosomal mutation of one of the four Mismatch Repair (MMR) genes, enunciated as MLH1, MSH2, MSH6 or PMS2, which can be discerned with cogent immune histochemical reactions or evaluation of Microsatellite Instability (MSI). Lynch syndrome is generally associated with a cumulative emergence of fewer than ten (
