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Casticin Mitigates Renal Damage Injured by Ischemia Reperfusion: A Biochemical Study
ISSN: 2687 - 5365
Publisher: author
Casticin Mitigates Renal Damage Injured by Ischemia Reperfusion: A Biochemical Study
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 3
Article Operation Score: 3
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: Necati Ozpinar
International Journal Address (IAA):
IAA.ZONE/2687103215365
eISSN
:
2687 - 5365
VALID
ISSN Validator
Abstract
Renal ischemia-reperfusion is a severe health condition that may be dangerous and even cause death. This research aims to search the protective effects of casticin on renal injury induced by ischemia-reperfusion. Study groups included sham, ischemia-reperfusion, 5 mg/kg casticin+ischemia reperfusion, and 10 mg/kg casticin+ischemia reperfusion groups. Some antioxidant, inflammatory, and oxidant parameters were examined in renal tissues obtained following the experiment. We found that the inflammatory and oxidant biomarkers elevated and antioxidants declined in the ischemia-reperfusion group. However, the antioxidant values raised, and inflammatory values declined in treatment groups. These results have shown us that casticin may be a potent molecule against oxidative renal damage following ischemia-reperfusion.
