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Evaluation of estrogenic potential of ethanolic and aqueous extract of Pitunia hybrida
ISSN: 2456 - 8244Publisher: author   
Evaluation of estrogenic potential of ethanolic and aqueous extract of Pitunia hybrida
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Biology and Life Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 3
Article Articles Score: 2
Article Accessibility Score: 2
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International Category Code (ICC):
ICC-0402
Publisher: Rb Science
International Journal Address (IAA):
IAA.ZONE/245695878244
eISSN
:
2456 - 8244
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Abstract
The objective of the present study was to assess the estrogenic potential of different leaf extract of Petunia hybrida using the animal model. The extraction ability of different solvents for recovering extractable components from leaves followed the order: ethanol>chloroform>aqueous>pet ether. The findings of preliminary phytochemical analysis suggest the presence of alkaloids, saponin glycosides, phenolics, terpenoids, sterols, and flavonoids in the leaf of the plant. The total phenolic content of pet ether, chloroform, ethanol and aqueous extracts of Petunia hybrida were 16.18±0.89, 23.97±0.61, 71.77±0.59 and 31.38±0.36 GAE mg/g, respectively. All the extracts were subjected to in vitro determination of antioxidant potential by DPPH method. The IC50 value of the DPPH scavenging potential for the chlorofom, ethanol and aqueous extracts was found to be 245.9, 115.2 and 181.3µg/mL respectively whereas the IC50 value of the pet ether e...