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Cuticular Biochemistry: Lambda-Cyhalothrin Induced Alterations in Mutant Drosophila melanogaster
ISSN: 0976 - 7614
Publisher: author
Cuticular Biochemistry: Lambda-Cyhalothrin Induced Alterations in Mutant Drosophila melanogaster
Indexed in
Biology and Life Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 2
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 3
Article Accessibility Score: 2
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-0402
Publisher: Journal Of Advanced Laboratory Research In Biology Society..
International Journal Address (IAA):
IAA.ZONE/097645077614
eISSN
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0976 - 7614
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ISSN Validator
Abstract
Derivatives of natural pyrethrum, synthetic pyrethroids, are well-established neurotoxins. However, they do interfere with the functioning of metabolic processes; the most important of these is chitin metabolism, a key process in the development of insects. Type II synthetic pyrethroid, lambda-cyhalothrin, when orally fed to Drosophila melanogaster revealed its efficacy in chitin synthesis modulation. Total proteins, glucosamine, N-acetylglucosamine, chitinase activity and chitin content exhibit significant changes in the final developmental stage, the adults. A reduction in chitin synthesis is suggestive of interference in polymerization process which is a must for cuticle formation. Involvement of lambda-cyhalothrin in chitin synthesis has been sought to be an additional mode of action, other than its neurotoxic nature.
