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Elevated PAPP-A Levels In Patients With Obstructive Sleep Apnea Syndrome
ISSN: 2687 - 5365
Publisher: author
Elevated PAPP-A Levels In Patients With Obstructive Sleep Apnea Syndrome
Indexed in
Medical Sciences
ARTICLE-FACTOR
1.3
Article Basics Score: 3
Article Transparency Score: 2
Article Operation Score: 2
Article Articles Score: 2
Article Accessibility Score: 3
SUBMIT PAPER ASK QUESTION
International Category Code (ICC):
ICC-1702
Publisher: International Journal Of Academic Medicne And Pharmacy Nec..
International Journal Address (IAA):
IAA.ZONE/268786065365
eISSN
:
2687 - 5365
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Abstract
Aim of this study was to evaluate serum concentration of Pregnancy-Associated Placental Protein-A (PAPP-A) in obstructive sleep apnea syndrome (OSAS) and to examine the relationship of PAPP-A with disease severity and body mass index (BMI). 60 OSAS patients and 21 control subjects included. All study participants were evaluated with polysomnograpic data, BMI, serum lipid, insulin, glucose and PAPP-A levels.PAPP-A values were higher in OSAS group than control group. When the groups were examined according to apnea-hypopnea index (AHI), PAPP-A level of severe OSAS group was determined to be significantly higher than that of control and mild and moderate OSAS groups. As the severity of OSAS increased, the level of PAPP-A increased. In ROC analysis applied to PAPP-A levels of the OSAS and control groups, the optimum cut-off point for serum PAPP-A levels in this study population was 2.38 ng/ml. A positive correlation was determined between...
